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How to Calculate Sample Size for Research

Too small a sample and your study lacks the power to detect a real effect. Too large, and you've wasted time and resources. Sample size calculation is how you find the number that's actually justified by your design — not a guess, and not "as many as I can get."

What determines your required sample size

  • Confidence level — how certain you want to be (typically 95%).
  • Margin of error — how much imprecision you'll accept in your estimate.
  • Expected variability — a proportion near 50% or a large standard deviation requires a bigger sample.
  • Effect size — for hypothesis-testing studies, smaller effects require larger samples to detect reliably.
  • Statistical power — typically set at 80% or 90%, the probability of detecting a real effect if one exists.

Two common approaches

For estimating a proportion or descriptive statistic: Cochran's formula, based on your desired confidence level and margin of error. Try our free Sample Size Calculator for this directly.

For hypothesis-testing or comparing groups: a power analysis, which additionally requires an expected effect size. This typically needs dedicated software (e.g., G*Power) rather than a simple formula, since the calculation differs by test type (t-test, ANOVA, regression, etc.).

Common mistakes

  • Skipping the calculation entirely and using a "round number" instead.
  • Using p=50% justification for a proportion you actually have prior data on (using the actual expected proportion gives a more efficient, often smaller, sample size).
  • Not accounting for expected dropout or non-response, leaving the study underpowered by the end.

Committees and journal reviewers increasingly expect a documented sample size justification, not just a final number.

Need a defensible sample size and power analysis for your specific design?

See Statistics Support